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457 studies · 142 with full dosimetry

Pain research

Musculoskeletal and joint pain trials.

Sorted newest first. The dose column is what the study actually delivered, which is the number to compare a device against. Rows without a recorded dose are excluded here because they cannot be matched to a protocol.

StudyYearλ nmDose J/cm²Sessions
Efficacy of home-based low-level laser therapy in patients with low back pain: a double-blinded randomized con
Wang · Lasers Med Sci
2026670, 780, 830, 9104.5915
Effect of class IV LASER therapy along with Low-dye kinesio-taping technique or plantar fascia stretching on p
Yadav · Lasers Med Sci
202698082
Efficacy of High-Intensity Laser Therapy Combined With Plantar Fascia Stretching Exercises in the Treatment of
Jitpimolmard · JMIR Rehabil Assist Technol
202610641209
Photobiomodulation with Structured Rehabilitation Improves Mechanical Function and Functional Aging in Degener
Ganguly · Photobiomodul Photomed Laser Surg
2026660, 810448
Effect of photobiomodulation on trapezius myofascial pain: a randomized, sham-controlled, double-blind clinica
do Nascimento Silva · Lasers Med Sci
2026808162.68
Comparative effects of low-level laser acupuncture and dry needling on clinical and functional outcomes in pat
Zaidi · Lasers Med Sci
2026830518
Targeting pain and inflammation: A comparative study of photobiomodulation with 532 and 660 nm lasers in rats
Mattoso-Câmara · Photochem Photobiol
2025532, 6601665
Multi-wave locked system laser therapy in chronic non-specific neck pain: a double-blind placebo randomized-co
Labanca · Eur J Phys Rehabil Med
2025808, 90558
Efficacy and safety of 650 nm invasive laser acupuncture on non-specific chronic low back pain: a randomized c
Hong · Front Med (Lausanne)
2025650382178
Single Application of Low-Level or Infrared Laser Therapy Not Effective in the Short Term for Neck Pain: A Ran
Ferreira · J Manipulative Physiol Ther
20258080.51
Efficacy of a wearable 660 nm red light therapy device in alleviating neck pain and enhancing neck function
Jiang · Lasers Med Sci
2025660486
Therapeutic synergy between swimming and photobiomodulation in a rat model of neuropathic pain
Araujo · Lasers Med Sci
20259046—
The Effect of Laser Biostimulation at Sensitized Acupoints on Chronic Pelvic Pain and Quality of Life in Women
Hasanin · Medicina (Kaunas)
20259041518
Comparison of low-level laser therapy versus neuromuscular electrical nerve stimulation at hemiplegic shoulder
Başaran & Büyükşireci · Lasers Med Sci
20259043—
Comparison of the Effectiveness of Low-Level Laser Therapy and Therapeutic Ultrasound in Patients with Rotator
Diyarbakır · J Clin Med
20258504—
Therapeutic Effects of Low-Level Laser Therapy on Pain and Disability of Patients with Failed Back Surgery Syn
Masoumipour · Indian J Orthop
2024808209
Outcomes of whole-body photobiomodulation on pain, quality of life, leisure physical activity, pain catastroph
Navarro-Ledesma · Front Neurosci
2024660, 85025.2—
Comparison of High-intensity Laser Therapy with Extracorporeal Shock Wave Therapy in the Treatment of Patients
Bidoki · Iran J Med Sci
202498089
The effect of high-intensity laser therapy on pain and lower extremity function in patellofemoral pain syndrom
Ozlu & Atilgan · Lasers Med Sci
202410641210
The effects of photobiomodulation and transcutaneous electrical nerve stimulation on chronic neck pain: A doub
Rampazo · Braz J Phys Ther
2024808128.5710
Effects of high and low level lasers on soreness following dry needling in patients with chronic myofascial ne
Motavalion · Lasers Med Sci
20248106—
Clinical Efficacy of Two Different Low-Level Laser Therapies for the Treatment of Trigeminal Neuralgia: A Rand
Karagözoğlu · J Clin Med
2024650, 904, 1064825
Systemic photobiomodulation in nursing professionals with chronic low back pain
Inocêncio · Rev Bras Med Trab
202366033—
Whole-Body Photobiomodulation Therapy for Fibromyalgia: A Feasibility Trial
Fitzmaurice · Behav Sci (Basel)
2023660, 85033.618
Low-level laser therapy versus ultrasound therapy combined with home-based exercise in patients with subacromi
Sen · Turk J Phys Med Rehabil
2023850315
Photobiomodulation self-treatment at home after rotator cuff arthroscopic repair accelerates improvement in pa
Abufoul · Lasers Surg Med
202380816.5—
Efficacy of invasive laser acupuncture in treating chronic non-specific low back pain: A randomized controlled
Kim · PLoS One
2022650, 830382178
Effects of photobiomodulation and deep water running in patients with chronic non-specific low back pain: a ra
Nardin · Lasers Med Sci
2022660, 8501.58
Extracorporeal Shock Wave Therapy Versus Low Level Laser Therapy in The Treatment of Plantar Fasciitis: A Rand
Timurtaş · J Am Podiatr Med Assoc
20228505.69
Efficacy of Low-Level Laser Therapy for the Treatment of Nonspecific Chronic Neck Pain: Low-Level Laser Therap
Momenzadeh · J Lasers Med Sci
20229801612
Feasibility study of a LED light irradiation device for the treatment of chronic neck with shoulder muscle pai
Odagiri · PLoS One
2022780571
Physiotherapeutic approach in seamstresses with neck pain: A single-blind, randomized clinical trial
De Toni · J Bodyw Mov Ther
202283020—
Photobiomodulation for Lowering Pain after Tonsillectomy: Low Efficacy and a Possible Unexpected Adverse Effec
Celsi · Life (Basel)
2022445, 660, 9706—
ET- B receptors involvement in peripheral opioid analgesia induced by light-emitting diode photobiomodulation
de Oliveira · J Photochem Photobiol B
20216302—
Comparative study of combination therapy with non-steroidal anti inflammatory drugs and different doses of low
Panah · J Bodyw Mov Ther
2021810312
Modulatory effects of photobiomodulation in the anterior cingulate cortex of diabetic rats
Rocha & Chacur · Photochem Photobiol Sci
20219046.23—
An Efficacy of Photobiomodulation of 850 nm on Pain Reduction in a Human Oral Capsaicin Pain Model
Sattayut · Photobiomodul Photomed Laser Surg
2021850301
Comparison of effects of low-level laser therapy and extracorporeal shock wave therapy in calcaneal spur treat
Güloğlu & Yalçın · Turk J Phys Med Rehabil
2021904815
Photobiomodulation as an Adjunctive Treatment to Physiotherapy for Reduction of Anterior Knee Pain in Combat S
Gavish · Lasers Surg Med
2021660, 810, 85038
Central involvement of 5-HT1A receptors in antinociception induced by photobiomodulation in animal model of ne
Santos · Lasers Med Sci
202180850—
A Randomized Comparative Study between High-Intensity and Low-Level Laser Therapy in the Treatment of Chronic
Abdelbasset · Evid Based Complement Alternat Med
2020850, 10645024
Photobiomodulation Therapy is Able to Modulate PGE2 Levels in Patients With Chronic Non-Specific Low Back Pain
Tomazoni · Lasers Surg Med
2020640, 875, 90531
Evaluation of the Therapeutic Effect of Low Level Laser in Controlling Low Back Pain: A Randomized Controlled
Kholoosy · J Lasers Med Sci
20208081.512
Evaluation Effects of Laser Therapy and Extracorporeal Shock Wave Therapy with Clinical Parameters and Magneti
Alpturker · Int J Rheumatol
2020830814
The Effect of High-Intensity Versus Low-Level Laser Therapy in the Management of Plantar Fasciitis: Randomized
Naruseviciute & Kubilius · Clin Rehabil
2020785, 106448
The Effectiveness of the Polarized Low-Level Laser in the Treatment of Patients With Myofascial Trigger Points
Shahimoridi · J Lasers Med Sci
2020755610
Effects of Dexamethasone and Low-Level Laser Therapy on Pain, Swelling, and Quality of Life After Buccal Fat P
Da Silva · J Oral Maxillofac Surg
2020660, 80823
Analgesic effect of Photobiomodulation Therapy: An in vitro and in vivo study.
Zupin · J Biophotonics
2019800, 9706—
Effect of laser treatment on postural control parameters in patients with chronic nonspecific low back pain: a
Taradaj · Braz J Med Biol Res
2019785, 1064815
Photobiomodulation-induced analgesia in experimental temporomandibular disorder involves central inhibition of
Ferrara-Jr · Lasers Med Sci
201966016—
A Comparative Study of Low-Level Laser Therapy and Transcutaneous Electrical Nerve Stimulation as an Adjunct t
Mansourian · Front Dent
2019810210
Low intensity photobiomodulation decreases neuropathic pain in paw ischemia-reperfusion and spared nervus isch
Pigatto · Pain Pract
201989020.8—
Efficacy of high-intensity laser therapy in subacromial impingement syndrome: a three-month follow-up controll
Aceituno-Gómez · Clin Rehabil
2019106430015
Pain management using photobiomodulation: mechanisms, location, and repeatability quantified by pain threshold
de Sousa · J Biophotonics
20188101.2—
Comparison of high-intensity laser therapy and combination of transcutaneous nerve stimulation and ultrasound
Kolu · Pak J Med Sci
2018106413210
Low-level laser therapy combined to functional exercise on treatment of fibromyalgia: a double-blind randomize
Germano Maciel · Lasers Med Sci
2018808142.8524
Botulinum toxin A (BT-A) versus low-level laser therapy (LLLT) in chronic migraine treatment: a comparison.
Loeb · Arq Neuropsiquiatr
201880812010
Comparison of effects of low-level laser therapy and extracorporeal shock wave therapy in plantar fasciitis tr
Yinilmez Sanmak · Turk J Phys Med Rehabil
2018685212
Combination Therapy Versus Exercise and Orthotic Support in the Management of Pain in Plantar Fasciitis: A Ran
Cinar · Foot Ankle Int
2018830, 850010
Comparative study of shockwave therapy and low-level laser therapy effects in patients with myofascial pain sy
Király · Rheumatol Int
2018808, 940315
Photobiostimulation reverses allodynia and peripheral nerve damage in streptozotocin-induced type 1 diabetes
Rocha · Lasers Med Sci
20179046.235
The effects of two different low level laser therapies in the treatment of patients with chronic low back pain
Koldaş Doğan · J Back Musculoskelet Rehabil
2017650, 785, 850, 9801015
Low Level Laser Therapy in patients with chronic foot and ankle joint pain.
Izukura · Laser Ther
201783020.18
Magnetic Resonance Imaging and Clinical Outcomes of Laser Therapy, Ultrasound Therapy, and Extracorporeal Shoc
Ulusoy · J Foot Ankle Surg
2017830815
Effectiveness of low-level laser therapy on pain intensity, pressure pain threshold, and SF-MPQ indexes of wom
Magri · Lasers Med Sci
201778058
Efficacy of Multiwave Locked System Laser on Pain and Function in Patients with Chronic Neck Pain: A Randomize
Alayat · Photomed Laser Surg
2017808, 830, 9054—
Low Level Laser Therapy alters satellite glial cell expression and reverses nociceptive behavior in rats with
Oliveira · Photochem Photobiol Sci
2017904610
The Antinociceptive Effect of Light-Emitting Diode Irradiation on Incised Wounds Is Correlated with Changes in
Chia · Pain Res Manag
20179404—
Transcranial low-level laser therapy (810 nm) temporarily inhibits peripheral nociception: photoneuromodulatio
Pires de Sousa · Neurophotonics
20168107.2—
Low-level laser therapy alleviates mechanical and cold allodynia induced by oxaliplatin administration in rats
Hsieh · Support Care Cancer
20167807.5—
Photobiomodulation of the dorsal root ganglion for the treatment of low back pain: A pilot study.
Holanda · Lasers Surg Med
201680828001
Light-emitting diode therapy reduces persistent inflammatory pain: Role of interleukin 10 and antioxidant enzy
Martins · Neuroscience
20169501—
Analgesic Effect of Photobiomodulation on Bothrops Moojeni Venom-Induced Hyperalgesia: A Mechanism Dependent o
Nadur-Andrade · PLoS Negl Trop Dis
20166852.21
Effects of 660nm low-level laser therapy on P2X3 expression of lumbar drg of adult male rats with neuropathic
Kerdari · Int Clin Neurosci J (not indexed in PubMed)
2016660414
Photobiomodulation therapy reduces apoptotic factors and increases glutathione levels in a neuropathic pain mo
Janzadeh · Lasers Med Sci
2016660414
Laser Acupuncture Treatment Improves Pain and Functional Status in Patients with Subacromial Impingement Syndr
Kibar · Pain Med
2016850415
Efficacy of low level laser therapy and intramuscular electrical stimulation on myofascial pain syndrome.
Sumen · J Back Musculoskelet Rehabil
2015670410
Effectiveness of occlusal splints and low-level laser therapy on myofascial pain.
Demirkol · Lasers Med Sci
20151064810
Effect of diode laser in the treatment of patients with nonspecific chronic low back pain: a randomized contro
Vallone · Photomed Laser Surg
201498037.59
Low-level laser therapy to treat fibromyalgia.
Ruaro · Lasers Med Sci
2014670412
Low-Level Laser Therapy for the Treatment of Chronic Plantar Fasciitis: A Prospective Study.
Jastifer · Foot Ankle Int
20146351.4766
Analgesic Effect of Light-Emitting Diode (LED) Therapy at Wavelengths of 635 and 945 nm on Bothrops moojeni Ve
Nadur-Andrade · Photochem Photobiol
2014635, 9453.76—
Antinociceptive action of Light Emitting Diode in an experimental model with hyperalgesia by capsaicin
Kerppers · MedicalExpress (Sáo Paulo)
20146277—
Comparison of low level laser, ultrasonic therapy and association in joint pain in Wistar rats.
Coradini · Rev Bras Reumatol
20148308—
Effects of 660- and 980-nm low-level laser therapy on neuropathic pain relief following chronic constriction i
Masoumipoor · Lasers Med Sci
2014660, 980414
Light-emitting diode therapy induces analgesia in a mouse model of postoperative pain through activation of pe
Cidral-Filho · Lasers Med Sci
20149501—
Low-level laser and local corticosteroid injection in the treatment of subacromial impingement syndrome: a con
Kelle & Kozanoglu · Clin Rehabil
201490429
The effect of low-level laser on postoperative pain after tibial fracture surgery: a double-blind controlled r
Nesioonpour · Anesth Pain Med
2014650, 80831
Effects of Class IV laser therapy on fibromyalgia impact and function in women with fibromyalgia
Panton · J Altern Complement Med
2013810, 98010.638
Effect of low level laser application at the end of surgery to reduce pain after tonsillectomy in adults.
Aghamohammadi · J Lasers Med Sci
201398041
Role of endogenous opioids in 820 nm low power laser analgesia in the knees of Wistar rats
Meireles · Rev Dor
20128208—
Evaluation of the effect of laser acupuncture and cupping with ryodoraku and visual analog scale on low back p
Lin · Evid Based Complement Alternat Med
2012808155
Use of low intensity laser treatment in neuropathic pain refractory to clinical treatment in amputation stumps
Ribas · Int J Gen Med
201283089
Effects of low-level laser therapy in combination with physiotherapy in the management of rotator cuff tendini
Eslamian · Lasers Med Sci
2012830410
Short-term effects of high-intensity laser therapy versus ultrasound therapy in the treatment of low back pain
Fiore · Eur J Phys Rehabil Med
201110640.7615
Chiropractic manipulative therapy and low-level laser therapy in the management of cervical facet dysfunction:
Saayman · J Manipulative Physiol Ther
20118305.576
Low level laser therapy (LLLT) for patients with sacroiliac joint pain.
Ohkuin · Laser Ther
20118302010
Low-level laser therapy, at 830 nm, for pain reduction in experimental model of rats with sciatica.
Bertolini · Arq Neuropsiquiatr
201183045
Additive effects of low-level laser therapy with exercise on subacromial syndrome: a randomised, double-blind,
Abrisham · Clin Rheumatol
2011890210
Influence of naloxone and methysergide on the analgesic effects of low-level laser in an experimental pain mod
Peres e Serra & Ashmawi · Rev Bras Anestesiol
20106602.5—
Acute low back pain with radiculopathy: a double-blind, randomized, placebo-controlled study.
Konstantinovic · Photomed Laser Surg
2010904315
Comparative analysis of analgesic efficacy of selected physiotherapy methods in low back pain patients.
Charlusz · Ortop Traumatol Rehabil
20108081210
Is low-level laser therapy effective in acute or chronic low back pain?
Ay · Clin Rheumatol
20108504015
Management of myofascial pain: low-level laser therapy versus occlusal splints.
Öz · J Craniofac Surg
2010820310
Low-level laser therapy for acute neck pain with radiculopathy: a double-blind placebo-controlled randomized s
Konstantinovic · Pain Med
2010905215
Evaluation of low intensity laser therapy in myofascial pain syndrome.
Carrasco · Cranio
2009780258
Low-level laser therapy in subacromial impingement syndrome.
Bal · Photomed Laser Surg
20099040.016510
Short-term effects of high-intensity laser therapy versus ultrasound therapy in the treatment of people with s
Santamato · Phys Ther
20091064205010
Analgesic action of laser therapy (LLLT) in an animal model.
Pozza · Med Oral Patol Oral Cir Bucal
2008660, 83010—
Low-power laser treatment in patients with frozen shoulder: preliminary results.
Stergioulas A · Photomed Laser Surg
20088103.612
GaAlAs (830 nm) low-level laser enhances peripheral endogenous opioid analgesia in rats.
Hagiwara · Lasers Surg Med
2007830200.73
In chronic low back pain, low level laser therapy combined with exercise is more beneficial than exercise alon
Djavid · Aust J Physiother
20078102712
Effectiveness of muscle stretching exercises with and without laser therapy at tender points for patients with
Matsutani · Clin Exp Rheumatol
2007830310
The effects of laser acupuncture on chronic tension headache--a randomised controlled trial.
Ebneshahidi · Acupunct Med
20058301310
Analgesic effect of He-Ne (632.8 nm) low-level laser therapy on acute inflammatory pain.
Ferreira · Photomed Laser Surg
20056332.53
Nociceptive scores and endorphin-containing cells reduced by low-level laser therapy (LLLT) in inflamed paws o
Laakso & Cabot · Photomed Laser Surg
20057801—
Low-power laser treatment for shoulder pain.
Bingöl · Photomed Laser Surg
20059042.9810
Efficacy of 904 nm gallium arsenide low level laser therapy in the management of chronic myofascial pain in th
Gur · Lasers Surg Med
2004904210
The effects of infrared laser and medical treatments on pain and serotonin degradation products in patients wi
Ceylan · Rheumatol Int
20049041.4410
Efficacy of low power laser therapy and exercise on pain and functions in chronic low back pain.
Gur · Lasers Surg Med
2003904120
Effects of low power laser and low dose amitriptyline therapy on clinical symptoms and quality of life in fibr
Gür · Rheumatol Int
2002904210
Efficacy of low power laser therapy in fibromyalgia: a single-blind, placebo-controlled trial.
Gür · Lasers Med Sci
2002904210
Low power laser therapy and analgesic action.
Tam G · J Clin Laser Med Surg
19999040.612
Failure to demonstrate any hypoalgesic effect of low intensity laser irradiation (830nm) of Erb's point upon e
Lowe · Lasers Surg Med
19978301.51
Cranial irradiation with Gaalas laser leads to naloxone reversible analgesia in rats.
Wedlock & Shephard · Psychol Rep
19968206.4—
Analgesic effects of cranial laser treatment in two rat nociception models.
Wedlock · Physiol Behav
19968206—
Acute cervical pain is relieved with gallium arsenide (GaAs) laser radiation. A double-blind preliminary study
Soriano · Laser Ther
1996904410
Can low reactive-level laser therapy be used in the treatment of neurogenic facial pain? A double-blind, place
Eckerdal & Bastian · Laser Ther
19968329.25
Double-blind, placebo-controlled investigation of the effect of combined phototherapy/low intensity laser ther
Mokhtar · Lasers Surg Med
1995660, 820, 880, 95031.9—
The efficacy of low-level laser therapy in supraspinatus tendinitis
Saunders L · Clin Rehabil
199582030—
Plasma acth and β-endorphin levels in response to low level laser therapy (lllt) for myofascial trigger points
Laakso · Laser Ther
1994660, 670, 82015
Report on a computer-randomized double blind clinical trial to determine the effectiveness of the gaalas (830
Toya · Laser Ther
1994830900—
LLLT (low reactive level laser therapy - a clinical study: relationship between pain attenuation and the serot
Mizokami · Laser Ther
1993633, 8309.9—
Retroactive study in 524 patients on the application of the 830 nm gaaias diode laser in low reactive-level la
Ohshiro & Shirono · Laser Ther
199283045—
Effect of semiconductor GaAs laser irradiation on pain perception in mice.
Zarković · Lasers Surg Med
19899050.0004—
Laser photobiomodulation is more effective than ultrasound therapy in patients with chronic nonspecific low ba
Tantawy · Lasers Med Sci
—80817.0516
The effect of high intensity laser therapy in the management of painful calcaneal spur: a double blind, placeb
Yesil · Lasers Med Sci
—10648.2615
Modulation of exercise-induced muscular damage and hyperalgesia by different 630 nm doses of light-emitting di
Vasconcelos · Lasers Med Sci
—6301.2—
Involvement of Substance P in the Analgesic Effect of Low-Level Laser Therapy in a Mouse Model of Chronic Wide
Han · Pain Med
—6858—
Effect of photobiomodulation therapy (808 nm) in the control of neuropathic pain in mice.
de Andrade · Lasers Med Sci
—8081038
Photobiomodulation therapy reduces acute pain and inflammation in mice.
Pigatto · J Photochem Photobiol B
—6602.531—
Antinociceptive effects of low-level laser therapy at 3 and 8 j/cm2 in a rat model of postoperative pain: poss
Pereira · Lasers Surg Med
—8301—

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