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🐁 Mouse · 2016 · Brazil (São Paulo)

Analgesic Effect of Photobiomodulation on Bothrops Moojeni Venom-Induced Hyperalgesia: A Mechanism Dependent on Neuronal Inhibition, Cytokines and Kinin Receptors Modulation.

Nadur-Andrade · PLoS Negl Trop Dis · 2016

The protocol this study used

Wavelength
685 nm
Dose
2.2 J/cm²
Sessions
1
Per session
15 sec

What the authors concluded

These data demonstrate that LLLT interferes with mechanisms involved in nociception and hyperalgesia and modulates Bmv-induced nociceptive signal. The use of photobiomodulation in reducing local pain induced by Bothropic venoms should be considered as a novel therapeutic tool for the treatment of local symptoms induced after bothropic snakebites.

Devices that emit this wavelength

Matched on wavelength within 15nm, since LED bins vary by roughly that much and a tighter match would be false precision. Where we have an irradiance figure, the session length is the time needed to reach this study's dose of 2.2 J/cm² at that intensity.

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MitoADAPT MAX 4.0
590 · 630 · 660 · 670 · 810 · 830 · 850 · 940 nm
Measured
$1,499
≈ 45 sec / session
at 49.4 mW/cm²
MitoADAPT MIN 4.0
590 · 630 · 660 · 670 · 810 · 830 · 850 · 940 nm
Measured
$549
≈ 54 sec / session
at 40.7 mW/cm²
Rouge Pro G4
630 · 650 · 660 · 670 · 810 · 830 · 850 · 1060 nm
Measured
$1,121
≈ 37 sec / session
at 59.2 mW/cm²
Theradome PRO LH80
680 nm
Brand claim
$845.99
no irradiance published
EMR-TEK Firewave
630 · 670 · 830 nm
Brand claim
$312.49
≈ 16 sec / session
at 138.39 mW/cm²
MitoADAPT MID 4.0
590 · 630 · 660 · 670 · 810 · 830 · 850 · 940 nm
Brand claim
$999
≈ 38 sec / session
at 58 mW/cm²

Matching a wavelength is not the same as reproducing a trial. Session times assume the device's published irradiance is accurate at the distance it was measured, which on brand-claim figures is often optimistic. Where a device publishes both a peak and an average we use the average, and where it publishes a falloff curve we use the lowest figure, so these times run long rather than short. Clinical protocols also control for spot size, contact and skin type in ways a home device cannot.

Source

PubMed 27749899 →

Dosimetry extracted by Vladimir Heiskanen in Photobiomodulation (PBM) research - a comprehensive database. Citation resolved against PubMed.