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257 studies · 103 with full dosimetry

Joints research

Knee, shoulder and joint-specific research.

Sorted newest first. The dose column is what the study actually delivered, which is the number to compare a device against. Rows without a recorded dose are excluded here because they cannot be matched to a protocol.

StudyYearλ nmDose J/cm²Sessions
Effect of photobiomodulation on fatigue-related errors in ankle joint position reproduction: the moderating ro
Ikuta · Lasers Med Sci
20268309.741
Photobiomodulation and extracellular vesicles-loaded alginate from adipose mesenchymal stem cells for cartilag
Hang · Int J Biol Macromol
20269043—
Photobiomodulation mitigates chondrocyte catabolism in osteoarthritis by modulating macrophage M1 polarization
Wang · J Orthop Surg Res
20258082.5224
Wavelength-dependent photobiomodulation attenuates synovial inflammation in fibroblast-like synoviocytes and a
Fan · J Photochem Photobiol B
2025625, 810, 940, 1050392
Additional effect of high-intensity laser therapy with conventional physiotherapy related to pain and function
Özgözen · Lasers Med Sci
202510649910
Photobiomodulation effects on synovial morphology, iNOS gene, and protein expression in a model of acute infla
do Bomfim · Acta Cir Bras
202480820—
Photobiomodulation associated with alginate-based engineered tissue on promoting chondrocytes-derived biologic
Hang · Int J Biol Macromol
20248302.5—
The Effects of High-Intensity Laser Therapy vs. Low-Level Laser Therapy on Functional Ability and Quadriceps A
Ezzati · J Lasers Med Sci
20248081210
Low-Level Laser Therapy for Thumb Carpometacarpal Joint Osteoarthritis: A Randomized Controlled Trial
Rahman · Cureus
2024830412
Effects of low-level laser therapy on acupuncture points on knee pain and function in knee osteoarthritis
Yetişir & Öztürk · Rev Assoc Med Bras (1992)
2023904415
Evaluation of the effect of high-intensity laser therapy (HILT) on function, muscle strength, range of motion,
Ekici & Ordahan · Lasers Med Sci
20231064129
Comparison between Low-Level and High-Intensity Laser Therapy as an Adjunctive Treatment for Knee Osteoarthrit
Ahmad · Life (Basel)
2023830, 10641012
Effects of low-level laser therapy and therapeutic ultrasound on Freund's complete adjuvant-induced knee arthr
Okur & Okumuş · Arch Rheumatol
20229051—
Resistance exercise and low-level laser therapy improves grip strength and morphological aspects in the ankle
Retameiro · Anat Rec (Hoboken)
20226605—
Photobiomodulation effects in metalloproteinases expression in zymosan-induced arthritis
Dos Anjos · Lasers Med Sci
20228303—
Short-Term Efficacy of High-Intensity Laser Therapy in Alleviating Pain in Patients with Knee Osteoarthritis:
Siriratna · Pain Res Manag
2022808, 90522.3910
Low-energy laser therapy application on knee joints as an auxiliary treatment in patients with polyarticular j
Elnaggar · Lasers Med Sci
20219037.536
High-frequency near-infrared diode laser irradiation suppresses IL-1β-induced inflammatory cytokine expression
Sakata · Lasers Med Sci
20219108—
Effects of photobiomodulation therapy in chondrocyte response by in vitro experiments and experimental model o
Tim · Lasers Med Sci
20218082824
Effects of photobiomodulation and a physical exercise program on the expression of inflammatory and cartilage
Vassão · Adv Rheumatol
20218089116
Effect of low-level laser irradiation on cytotoxicity of benzene in human normal fibroblast cells
Salemi · Lasers Med Sci
20216603—
Photobiomodulation and Sida tuberculata combination declines the inflammation's markers in knee-induced osteoa
Yamada · Lasers Med Sci
202190493
Photobiomodulation Therapy (Light Emitting Diode 630 nm) Favored the Oxidative Stress and the Preservation of
Martins · Photobiomodul Photomed Laser Surg
20216309—
Photobiomodulation (λ=808nm) and Platelet-Rich Plasma (PRP) for the Treatment of Acute Rheumatoid Arthritis in
Gonçalves · J Lasers Med Sci
2021808301
High-Frequency Near-Infrared Diode Laser Irradiation Attenuates IL-1β-Induced Expression of Inflammatory Cytok
Sakata · J Clin Med
20209104—
Efficacy of high intensity laser therapy in knee osteoarthritis: a double-blind controlled randomized study
Akaltun · Clin Rheumatol
202010641210
Preliminary Clinical Experience of Low-Level Laser Therapy for the Treatment of Canine Osteoarthritis-Associat
Barale · Open Vet J
20208084.26
Exercise program combined with electrophysical modalities in subjects with knee osteoarthritis: a randomised,
de Paula Gomes · BMC Musculoskelet Disord
2020904624
Level of pain, muscle strength and posture: effects of PBM on an exercise program in women with knee osteoarth
Vassão · Lasers Med Sci
20208089116
Evaluation of metalloproteinases-2, -9, and -13 post photobiomodulation in mice talocrural joint.
Abduch · Lasers Med Sci
20198303—
Effects of low-level laser therapy on the organization of articular cartilage in an experimental microcrystall
Felizatti · Lasers Med Sci
2019830187
Photobiomodulation Therapy Partially Restores Cartilage Integrity and Reduces Chronic Pain Behavior in a Rat M
Balbinot · Cartilage
201985057.14—
Photobiomodulation therapy in knee osteoarthritis reduces oxidative stress and inflammatory cytokines in rats.
Yamada · J Biophotonics
20199046—
Efficacy of high-intensity laser therapy in comparison with conventional physiotherapy and exercise therapy on
Nazari · Lasers Med Sci
201910646012
Photobiomodulation via a cluster device associated with a physical exercise program in the level of pain and m
Vassão · Lasers Med Sci
20198089116
Physical exercise and low-level laser therapy on the nociception and leukocyte migration of Wistar rats submit
Neves · Lasers Med Sci
20196605—
Modulation of immune response to induced-arthritis by low-level laser therapy.
Dos Anjos · J Biophotonics
20188303—
Interleukin-10 and collagen type II immunoexpression are modulated by photobiomodulation associated to aerobic
Assis · Lasers Med Sci
201880850—
The effect of low-level laser therapy and physical exercise on pain, stiffness, function, and spatiotemporal g
de Matos Brunelli Braghin · Disabil Rehabil
201880820015
A randomized blind placebo-controlled trial investigating the effects of photobiomodulation therapy (PBMT) on
Looney · Can Vet J
2018650, 980109
Incorporation of photobiomodulation therapy into a therapeutic exercise program for knee osteoarthritis: A pla
de Paula Gomes · Lasers Surg Med
2018640, 875, 905110
Can photobiomodulation associated with implantation of mesenchymal adipose-derived stem cells attenuate the ex
Stancker · Lasers Med Sci
201880871.2—
Ultrasound plus low-level laser therapy for knee osteoarthritis rehabilitation: a randomized, placebo-controll
Paolillo · Rheumatol Int
2018808712
Long-Term Effect of Pulsed Nd:YAG Laser in the Treatment of Children with Juvenile Rheumatoid Arthritis: A Ran
El-Shamy · Photomed Laser Surg
201810641012
Low-intensity laser therapy efficacy evaluation in mice subjected to acute arthritis condition.
Trawitzki · J Photochem Photobiol B
2017660, 808, 90551
Efficacy of pulsed Nd:YAG laser in the treatment of patients with knee osteoarthritis: a randomized controlled
Alayat · Lasers Med Sci
201710641.4312
Photobiomodulation therapy in the modulation of inflammatory mediators and bradykinin receptors in an experime
de Oliveira · Lasers Med Sci
2017808144—
Photobiomodulation therapy associated with treadmill training in the oxidative stress in a collagen-induced ar
Dos Santos · Lasers Med Sci
201780871.415
Effectiveness of High Intensity Laser Therapy for Reduction of Pain in Knee Osteoarthritis.
Angelova & Ilieva · Pain Res Manag
20161064127
Aerobic exercise training and low-level laser therapy modulate inflammatory response and degenerative process
Assis · Osteoarthritis Cartilage
20168085024
Effect of Laser Therapy on Chronic Osteoarthritis of the Knee in Older Subjects.
Youssef · J Lasers Med Sci
2016880, 904616
Isolated and combined effects of photobiomodulation therapy, topical nonsteroidal anti-inflammatory drugs, and
Tomazoni · J Biomed Opt
2016830214.224
Effects of photobiomodulation therapy, pharmacological therapy, and physical exercise as single and/or combine
Tomazoni · Lasers Med Sci
2016830214.224
Synergic effects of ultrasound and laser on the pain relief in women with hand osteoarthritis.
Paolillo · Lasers Med Sci
2015808712
Musculoskeletal Atrophy in an Experimental Model of Knee Osteoarthritis: The Effects of Exercise Training and
Assis · Am J Phys Med Rehabil
20158085024
Short-term efficacy of low-level laser therapy in patients with knee osteoarthritis: a randomized placebo-cont
Fukuda · Rev Bras Ortop
201590439
The fluence effects of low-level laser therapy on inflammation, fibroblast-like synoviocytes, and synovial apo
Hsieh · Photomed Laser Surg
20147804.510
Protective effect of low-level laser therapy (LLLT) on acute zymosan-induced arthritis.
Carlos · Lasers Med Sci
20146602.5—
Monochromatic Infrared Photo Energy versus Low Level Laser Therapy in Patients with Knee Osteoarthritis.
Ammar TA · J Lasers Med Sci
2014850, 89062.412
Therapeutic effect of irradiation of magnetic infrared laser on osteoarthritis rat model.
Moon · Photochem Photobiol
20148501.33—
The effect of low-level laser therapy on knee osteoarthritis: prospective, descriptive study.
Soleimanpour · Lasers Med Sci
2014810, 890612
Effect of low-level laser therapy on metalloproteinase MMP-2 and MMP-9 production and percentage of collagen t
Alves · Lasers Med Sci
20148081424
High-intensity versus low-level laser therapy in the treatment of patients with knee osteoarthritis: a randomi
Kheshie · Lasers Med Sci
2014830, 10645012
Effects of low-level laser therapy on joint pain, synovitis, anabolic, and catabolic factors in a progressive
Wang · Lasers Med Sci
20148301.524
Efficacy of low-level laser therapy applied at acupuncture points in knee osteoarthritis: a randomised double-
Al Rashoud · Physiotherapy
201483049
Comparative analysis of two low-level laser doses on the expression of inflammatory mediators and on neutrophi
dos Santos · Lasers Med Sci
201480871.41
Anti-inflammatory activities of light emitting diode irradiation on collagen-induced arthritis in mice (a seco
Kuboyama · Laser Ther
2014570, 940524
Pulsed versus continuous wave low-level light therapy on osteoarticular signs and symptoms in limited sclerode
Barolet D · J Biomed Opt
2014940812
Effect of low-level laser therapy on the expression of inflammatory mediators and on neutrophils and macrophag
Alves · Arthritis Res Ther
2013808142.41
Low-level laser therapy in different stages of rheumatoid arthritis: a histological study.
Alves · Lasers Med Sci
20137807.77
Effects of Low-Level Laser Therapy, 660 nm, in Experimental Septic Arthritis.
Araujo · ISRN Rheumatol
20136602—
Infrared (810-nm) low-level laser therapy on rat experimental knee inflammation.
Pallotta · Lasers Med Sci
2012810501
Influence of various laser therapy methods on knee joint pain and function in patients with knee osteoarthriti
Gworys · Ortop Traumatol Rehabil
2012808, 810, 90512.710
Therapeutic effects of short-term monochromatic infrared energy therapy on patients with knee osteoarthritis:
Hsieh · J Orthop Sports Phys Ther
201289083.26
Short-term effects of 890-nanometer radiation on pain, physical activity, and postural stability in patients w
Hsieh · Arch Phys Med Rehabil
201289041.66
Reduction of monocyte chemoattractant protein-1 expression in rheumatoid arthritis rat joints with light-emitt
Kuboyama & Abiko · Laser Ther
201284026
Effect of light-emitting diode (LED) therapy on the development of osteoarthritis (OA) in a rabbit model.
Oshima · Biomed Pharmacother
2011630, 8702.425
Reduction of CXCR4 expression in Rheumatoid Arthritis Rat Joints by low level diode laser irradiation.
Zhang · Laser Ther
20118305—
Anti-inflammatory effect of low-level laser and light-emitting diode in zymosan-induced arthritis.
de Morais · Photomed Laser Surg
2010628, 685, 8302.5—
Effect of GaAlAs laser irradiation on the epiphyseal cartilage of rats
Cressoni · Photomed Laser Surg
20108305—
Helium-neon laser reduces the inflammatory process of arthritis.
Rubio · Photomed Laser Surg
20106338—
Assessment of the effectiveness of low-level laser therapy on the hands of patients with rheumatoid arthritis:
Meireles · Clin Rheumatol
2010785316
Inflammatory and oxidative stress markers in experimental crystalopathy: their modification by photostimulatio
Rubio · Photomed Laser Surg
200963383
The effect of low-level laser in knee osteoarthritis: a double-blind, randomized, placebo-controlled trial.
Hegedus · Photomed Laser Surg
2009830488
Low-level laser therapy for zymosan-induced arthritis in rats: Importance of illumination time.
Castano · Lasers Surg Med
200781035
Low-power laser stimulation of tissue engineered cartilage tissue formed on a porous calcium polyphosphate sca
Gan · Lasers Surg Med
20076501.7528
Effect of low-level helium-neon laser therapy on histological and ultrastructural features of immobilized rabb
Bayat · J Photochem Photobiol B
20076331321
Photobiomodulation of pain and inflammation in microcrystalline arthropathies: experimental and clinical resul
Soriano · Photomed Laser Surg
2006633, 90483
Randomized controlled trial on low level laser therapy (LLLT) in the treatment of osteoarthritis (OA) of the h
Brosseau · Lasers Surg Med
2005860318
Assessment of low-power laser biostimulation on chondral lesions: an "in vivo" experimental study.
Guzzardella · Artif Cells Blood Substit Immobil Biotechnol
2000780300—
Beneficial effects of laser therapy in the early stages of rheumatoid arthritis onset
Ailioaie & Lupusoru-Ailioaie · Laser Ther
1999830232
Low Intensity Laser and Phototherapy for Rheumatoid Arthritis
Goats · Physiotherapy
1996660, 9508.18
The analgesic effect of 904 nm gallium arsenide semiconductor low level laser therapy (LLLT) on osteoarticular
Soriano · Laser Ther
1995904610
Low level laser therapy is ineffective in the management of rheumatoid arthritic finger joints.
Hall · Br J Rheumatol
1994820, 870, 880, 9503612
A double blind randomised trial of low power laser treatment in rheumatoid arthritis.
Heussler · Ann Rheum Dis
19938201212
Histological effects of 820 nm laser irradiation on the healthy growth plate of the rat
Cheetham · Laser Ther
199282056
Infrared diode laser in low reactive-level laser therapy (lllt) for knee osteoarthrosis
Trelles · Laser Ther
1991830188
Low-power laser therapy in rheumatoid arthritis
Palmgren · Lasers Med Sci
19898203.5812
Soft-laser therapy of rheumatoid arthritis.
Bliddal · Scand J Rheumatol
198763369
Laser therapy of rheumatoid arthritis.
Goldman · Lasers Surg Med
198010601510
Low-intensity laser therapy efficacy evaluation in FVB mice subjected to acute and chronic arthritis.
Issa · Lasers Med Sci
—660, 808, 9055—
Apoptosis induced by low-level laser in polymorphonuclear cells of acute joint inflammation: comparative analy
Dos Anjos · Lasers Med Sci
—8303—
Chondroitin sulfate and glucosamine sulfate associated to photobiomodulation prevents degenerative morphologic
Sanches · Lasers Med Sci
—8085029

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