Effects of 660nm low-level laser therapy on P2X3 expression of lumbar drg of adult male rats with neuropathic pain

What the authors concluded

↑Bcl2, ↑GSH, ↓Bax, ↓P2X3, ↓mechanical and thermal threshold "Based on our findings, the therapeutic effects of LLLT for NP act throughout cellular and molecular mechanisms which improve mitochondrial function that in turn improve cell function and prevent apoptosis. " Comment: According to methods section, they also used a NIR laser, but the paper doesn't include any kind of a description of the

Devices that emit this wavelength

Matched on wavelength within 15nm, since LED bins vary by roughly that much and a tighter match would be false precision. Where we have an irradiance figure, the session length is the time needed to reach this study's dose of 4 J/cm² at that intensity.

Matching a wavelength is not the same as reproducing a trial. Session times assume the device's published irradiance is accurate at the distance it was measured, which on brand-claim figures is often optimistic. Where a device publishes both a peak and an average we use the average, and where it publishes a falloff curve we use the lowest figure, so these times run long rather than short. Clinical protocols also control for spot size, contact and skin type in ways a home device cannot.