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🧪 In vitro · 2021 · Iran (Tehran)

Effect of low-level laser irradiation on cytotoxicity of benzene in human normal fibroblast cells

Salemi · Lasers Med Sci · 2021

The protocol this study used

Wavelength
660 nm
Dose
3 J/cm²
Sessions
—
Per session
1 min 30 sec

What the authors concluded

The effect of low-level laser therapy on the viability of the cells was positive at concentrations 0-15 μg/mL but negative at higher concentrations than 15 μg/mL." "Low-level laser therapy in low concentrations of benzene decreases the cytotoxicity caused by benzene and maintains cell viability. At high concentrations and in the presence of low-level laser therapy, the cell viability decreased c

Devices that emit this wavelength

Matched on wavelength within 15nm, since LED bins vary by roughly that much and a tighter match would be false precision. Where we have an irradiance figure, the session length is the time needed to reach this study's dose of 3 J/cm² at that intensity.

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MitoPRO 1500+
630 · 660 · 830 · 850 nm
Measured
$1,169
≈ 39 sec / session
at 76.5 mW/cm²
MitoPRO 1500X
590 · 630 · 660 · 810 · 830 · 850 nm
Measured
$1,299
≈ 56 sec / session
at 53.5 mW/cm²
PlatinumLED BIOMAX 900
480 · 630 · 660 · 810 · 830 · 850 · 1060 nm
Measured
$1,299
≈ 33 sec / session
at 90.3 mW/cm²
HoogaHealth PRO1500
660 · 850 nm
Measured
$1,199
≈ 35 sec / session
at 86 mW/cm²
Joovv Solo 3.0
660 · 850 nm
Measured
$1,499
≈ 51 sec / session
at 59.2 mW/cm²
LUMEBOX 2.0
660 · 850 nm
Measured
$629
≈ 24 sec / session
at 125 mW/cm²

Matching a wavelength is not the same as reproducing a trial. Session times assume the device's published irradiance is accurate at the distance it was measured, which on brand-claim figures is often optimistic. Where a device publishes both a peak and an average we use the average, and where it publishes a falloff curve we use the lowest figure, so these times run long rather than short. Clinical protocols also control for spot size, contact and skin type in ways a home device cannot.

Source

PubMed 33415460 →

Dosimetry extracted by Vladimir Heiskanen in Photobiomodulation (PBM) research - a comprehensive database. Citation resolved against PubMed.