🐀 Rat 🧑 Human (acute gout arthritis) 🎲 Randomized trial 👥 25 participants ⌛ 5-day treatment 🧑 Human (chronic pyrophosph. arthrop.) 🎲 Randomized trial 👥 49 participants ⌛ 21-day treatment 🧑 Human (shoulder apatite deposition) 🎲 Randomized trial 👥 30 participants ⌛ 21-day treatment · 2006 · Argentina (Rosario)
Photobiomodulation of pain and inflammation in microcrystalline arthropathies: experimental and clinical results.
Soriano · Photomed Laser Surg · 2006
The protocol this study used
What the authors concluded
Fibrinogen, prostaglandin E(2), and TNF(alpha) concentrations in the rats injected with crystals and treated with laser decreased significantly as compared with the groups injected with crystals without treatment." "Both laser therapy and diclofenac achieved rapid pain relief in patients with acute gouty arthritis without significant differences in efficacy. Laser therapy was more effective than
Devices that emit this wavelength
Matched on wavelength within 15nm, since LED bins vary by roughly that much and a tighter match would be false precision. Where we have an irradiance figure, the session length is the time needed to reach this study's dose of 8 J/cm² at that intensity.
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Matching a wavelength is not the same as reproducing a trial. Session times assume the device's published irradiance is accurate at the distance it was measured, which on brand-claim figures is often optimistic. Where a device publishes both a peak and an average we use the average, and where it publishes a falloff curve we use the lowest figure, so these times run long rather than short. Clinical protocols also control for spot size, contact and skin type in ways a home device cannot.
Source
Dosimetry extracted by Vladimir Heiskanen in Photobiomodulation (PBM) research - a comprehensive database. Citation resolved against PubMed.