🧑 Human 📄 Controlled, non-randomized trial, sham-controlled 👥 22 participants ⌛ 30 days · 2020 · Brazil (Paraná)
Study of transcranial photobiomodulation at 945-nm wavelength: anxiety and depression.
Kerppers · Lasers Med Sci · 2020
The protocol this study used
What the authors concluded
The 945-nm LED transcranial photobiomodulation improves brain activity and may clinically decrease anxiety and depression." Comment: The paper is somewhat strangely written, and it seems that the between-the-groups changes (before-after) haven't been tested for statistical significance.
Devices that emit this wavelength
Matched on wavelength within 15nm, since LED bins vary by roughly that much and a tighter match would be false precision. Where we have an irradiance figure, the session length is the time needed to reach this study's dose of 9.35 J/cm² at that intensity.
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Matching a wavelength is not the same as reproducing a trial. Session times assume the device's published irradiance is accurate at the distance it was measured, which on brand-claim figures is often optimistic. Where a device publishes both a peak and an average we use the average, and where it publishes a falloff curve we use the lowest figure, so these times run long rather than short. Clinical protocols also control for spot size, contact and skin type in ways a home device cannot.
Source
Dosimetry extracted by Vladimir Heiskanen in Photobiomodulation (PBM) research - a comprehensive database. Citation resolved against PubMed.