🧑 Human 📄 Case series 👥 3 cases ⌛ 4-8 weeks · 2019 · Italy (Cagliari)
Transcranial Photobiomodulation for Down Syndrome.
Mannu · Photobiomodul Photomed Laser Surg · 2019
The protocol this study used
What the authors concluded
Although no quantitative measures were implemented, the following qualitative changes were reported: (1) improved dexterity (fine motor skills) was reported by the caregivers and also demonstrated by more accurate copying of drawings (spiral drawing test) and by more detailed portraits’ drawings (Fig. 2). (2) Improved verbal fluency (speaking in full sentences) paired with greater attention,
Devices that emit this wavelength
Matched on wavelength within 15nm, since LED bins vary by roughly that much and a tighter match would be false precision. Where we have an irradiance figure, the session length is the time needed to reach this study's dose of 40 J/cm² at that intensity.
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Matching a wavelength is not the same as reproducing a trial. Session times assume the device's published irradiance is accurate at the distance it was measured, which on brand-claim figures is often optimistic. Where a device publishes both a peak and an average we use the average, and where it publishes a falloff curve we use the lowest figure, so these times run long rather than short. Clinical protocols also control for spot size, contact and skin type in ways a home device cannot.
Source
Dosimetry extracted by Vladimir Heiskanen in Photobiomodulation (PBM) research - a comprehensive database. Citation resolved against PubMed.