Transcranial photobiomodulation ameliorates hypobaric hypoxia-induced spatial cognitive dysfunction by enhancing synaptic plasticity

What the authors concluded

Barnes maze performance demonstrated that tPBM significantly ameliorated HH-induced deficits in spatial learning and memory. Mechanistically, tPBM modulated hemodynamic responses and enhanced cerebral oxygen-binding efficiency within the lateral parietal association cortex (LPtA). Furthermore, tPBM improved mitochondrial function by elevating cytochrome c oxidase activity and promoting ATP sy

Devices that emit this wavelength

Matched on wavelength within 15nm, since LED bins vary by roughly that much and a tighter match would be false precision. Where we have an irradiance figure, the session length is the time needed to reach this study's dose of 4 J/cm² at that intensity.

Matching a wavelength is not the same as reproducing a trial. Session times assume the device's published irradiance is accurate at the distance it was measured, which on brand-claim figures is often optimistic. Where a device publishes both a peak and an average we use the average, and where it publishes a falloff curve we use the lowest figure, so these times run long rather than short. Clinical protocols also control for spot size, contact and skin type in ways a home device cannot.