🐀 Rat · 2017 · Brazil (Guarapuava)
Transcranial LED therapy on amyloid-β toxin 25-35 in the hippocampal region of rats.
da Luz Eltchechem · Lasers Med Sci · 2017
The protocol this study used
What the authors concluded
Our study indicates the beneficial effect of PBM treatment on behavioral tasks in the early stages of AD by demonstrating the improvement in motor and behavioral performance in treated animals compared to nontreated ones." "The use of PBM in rats with AD showed a significant reduction in senile plaques after 21 days of treatment in the treated group compared to the nontreated group." "The early
Devices that emit this wavelength
Matched on wavelength within 15nm, since LED bins vary by roughly that much and a tighter match would be false precision. Where we have an irradiance figure, the session length is the time needed to reach this study's dose of 7 J/cm² at that intensity.
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Matching a wavelength is not the same as reproducing a trial. Session times assume the device's published irradiance is accurate at the distance it was measured, which on brand-claim figures is often optimistic. Where a device publishes both a peak and an average we use the average, and where it publishes a falloff curve we use the lowest figure, so these times run long rather than short. Clinical protocols also control for spot size, contact and skin type in ways a home device cannot.
Source
Dosimetry extracted by Vladimir Heiskanen in Photobiomodulation (PBM) research - a comprehensive database. Citation resolved against PubMed.