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🧑 Human 🎲 Randomized trial 👥 32 participants ⌛ 12 weeks (after chemotherapy) · 2023 · Belgium (Hasselt)

The use of photobiomodulation therapy for the management of chemotherapy-induced alopecia: a randomized, controlled trial (HAIRLASER trial)

Lodewijckx · Support Care Cancer · 2023

The protocol this study used

Wavelength
678 nm
Dose
1.03 J/cm²
Sessions
36
Per session
20 min

What the authors concluded

Significantly higher NRS scores were observed in the PBM group at 1-month post-chemotherapy compared to baseline, whereas they remained constant in the control group. Patients allocated to the PBM group scored their global health significantly higher at all time points compared to the control." Comment: The difference in hair growth was significant at month 1 but not month 2 or month 3. Slight b

Devices that emit this wavelength

Matched on wavelength within 15nm, since LED bins vary by roughly that much and a tighter match would be false precision. Where we have an irradiance figure, the session length is the time needed to reach this study's dose of 1.03 J/cm² at that intensity.

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MitoADAPT MAX 4.0
590 · 630 · 660 · 670 · 810 · 830 · 850 · 940 nm
Measured
$1,499
≈ 21 sec / session
at 49.4 mW/cm²
MitoADAPT MIN 4.0
590 · 630 · 660 · 670 · 810 · 830 · 850 · 940 nm
Measured
$549
≈ 25 sec / session
at 40.7 mW/cm²
Rouge Pro G4
630 · 650 · 660 · 670 · 810 · 830 · 850 · 1060 nm
Measured
$1,121
≈ 17 sec / session
at 59.2 mW/cm²
Theradome PRO LH80
680 nm
Brand claim
$845.99
no irradiance published
EMR-TEK Firewave
630 · 670 · 830 nm
Brand claim
$312.49
≈ 7 sec / session
at 138.39 mW/cm²
MitoADAPT MID 4.0
590 · 630 · 660 · 670 · 810 · 830 · 850 · 940 nm
Brand claim
$999
≈ 18 sec / session
at 58 mW/cm²

Matching a wavelength is not the same as reproducing a trial. Session times assume the device's published irradiance is accurate at the distance it was measured, which on brand-claim figures is often optimistic. Where a device publishes both a peak and an average we use the average, and where it publishes a falloff curve we use the lowest figure, so these times run long rather than short. Clinical protocols also control for spot size, contact and skin type in ways a home device cannot.

Source

PubMed 37060420 →

Dosimetry extracted by Vladimir Heiskanen in Photobiomodulation (PBM) research - a comprehensive database. Citation resolved against PubMed.