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🧑 Human 🎲 Randomized trial 👥 20 participants ⌛ 4 weeks + Ex vivo · 2025 · ?

The Use of a Proprietary Near-Infrared Laser to Enhance Wound Healing: A Preliminary Preclinical and Clinical Study

Glas · Aesthet Surg J Open Forum · 2025

The protocol this study used

Wavelength
808, 810 nm
Dose
56 J/cm²
Sessions
3
Per session
3 min

What the authors concluded

The laser altered expression of 45 genes. Highly up-regulated genes (>5-fold change) included those implicated in wound healing and antiaging, whereas highly down-regulated genes included those implicated in inflammation and extracellular matrix integrity. The LED device altered expression of only 1 gene relative to negative controls." "The laser reduced mean wound area by 78% and healed 4 of 10

Devices that emit this wavelength

Matched on wavelength within 15nm, since LED bins vary by roughly that much and a tighter match would be false precision. Where we have an irradiance figure, the session length is the time needed to reach this study's dose of 56 J/cm² at that intensity.

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MitoPRO 1500X
590 · 630 · 660 · 810 · 830 · 850 nm
Measured
$1,299
≈ 17 min 27 sec / session
at 53.5 mW/cm²
PlatinumLED BIOMAX 900
480 · 630 · 660 · 810 · 830 · 850 · 1060 nm
Measured
$1,299
≈ 10 min 20 sec / session
at 90.3 mW/cm²
MitoADAPT MAX 4.0
590 · 630 · 660 · 670 · 810 · 830 · 850 · 940 nm
Measured
$1,499
≈ 18 min 54 sec / session
at 49.4 mW/cm²
MitoADAPT MIN 4.0
590 · 630 · 660 · 670 · 810 · 830 · 850 · 940 nm
Measured
$549
≈ 22 min 56 sec / session
at 40.7 mW/cm²
PlatinumLED BIOMAX 300
480 · 630 · 660 · 810 · 830 · 850 · 1060 nm
Measured
$659
≈ 13 min 20 sec / session
at 70 mW/cm²
Infraredi Pro Max 2.0
630 · 660 · 810 · 830 · 850 nm
Measured
$959
≈ 12 min 58 sec / session
at 72 mW/cm²

Matching a wavelength is not the same as reproducing a trial. Session times assume the device's published irradiance is accurate at the distance it was measured, which on brand-claim figures is often optimistic. Where a device publishes both a peak and an average we use the average, and where it publishes a falloff curve we use the lowest figure, so these times run long rather than short. Clinical protocols also control for spot size, contact and skin type in ways a home device cannot.

Source

PubMed 40201332 →

Dosimetry extracted by Vladimir Heiskanen in Photobiomodulation (PBM) research - a comprehensive database. Citation resolved against PubMed.