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🧪 In vitro · 2014 · Japan (Kobe)

The long-term effects of red light-emitting diode irradiation on the proliferation and differentiation of osteoblast-like MC3T3-E1 cells.

Asai · Kobe J Med Sci · 2014

The protocol this study used

Wavelength
630 nm
Dose
0.5 J/cm²
Sessions
—
Per session
—

What the authors concluded

The number of viable MC3T3-E1 cells showed a tendency to increase after the irradiation at all three energy densities in comparison with a non-irradiation group (control group). In particular, there was a remarkable 3.34-fold increase in the group irradiated with 3.0J/cm² on day 7 after starting the culture. On culture day 15, there was a tendency for the red LED irradiation group (0.5 J/cm²) to

Devices that emit this wavelength

Matched on wavelength within 15nm, since LED bins vary by roughly that much and a tighter match would be false precision. Where we have an irradiance figure, the session length is the time needed to reach this study's dose of 0.5 J/cm² at that intensity.

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Measured
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≈ 10 sec / session
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at 40.7 mW/cm²
PlatinumLED BIOMAX 300
480 · 630 · 660 · 810 · 830 · 850 · 1060 nm
Measured
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≈ 7 sec / session
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Matching a wavelength is not the same as reproducing a trial. Session times assume the device's published irradiance is accurate at the distance it was measured, which on brand-claim figures is often optimistic. Where a device publishes both a peak and an average we use the average, and where it publishes a falloff curve we use the lowest figure, so these times run long rather than short. Clinical protocols also control for spot size, contact and skin type in ways a home device cannot.

Source

PubMed 25011637 →

Dosimetry extracted by Vladimir Heiskanen in Photobiomodulation (PBM) research - a comprehensive database. Citation resolved against PubMed.