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🧪 In vitro · 2024 · Taiwan (Taipei)

Synergistic effects of platelet-rich fibrin and photobiomodulation on bone regeneration in MC3T3-E1 Preosteoblasts

Chou · Photodiagnosis Photodyn Ther · 2024

The protocol this study used

Wavelength
830 nm
Dose
5 J/cm²
Sessions
—
Per session
—

What the authors concluded

The combination of PRF and PBM significantly improved cell viability, migration, and calcium deposition, with the most notable effects observed after seven and fourteen days. However, a slight decrease in calcium deposition was noted in the 100 % PRF combined with the PBM group, suggesting a potential feedback mechanism at higher PRF concentrations.

Devices that emit this wavelength

Matched on wavelength within 15nm, since LED bins vary by roughly that much and a tighter match would be false precision. Where we have an irradiance figure, the session length is the time needed to reach this study's dose of 5 J/cm² at that intensity.

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MitoPRO 1500+
630 · 660 · 830 · 850 nm
Measured
$1,169
≈ 65 sec / session
at 76.5 mW/cm²
MitoPRO 1500X
590 · 630 · 660 · 810 · 830 · 850 nm
Measured
$1,299
≈ 1 min 33 sec / session
at 53.5 mW/cm²
PlatinumLED BIOMAX 900
480 · 630 · 660 · 810 · 830 · 850 · 1060 nm
Measured
$1,299
≈ 55 sec / session
at 90.3 mW/cm²
MitoADAPT MAX 4.0
590 · 630 · 660 · 670 · 810 · 830 · 850 · 940 nm
Measured
$1,499
≈ 1 min 41 sec / session
at 49.4 mW/cm²
MitoADAPT MIN 4.0
590 · 630 · 660 · 670 · 810 · 830 · 850 · 940 nm
Measured
$549
≈ 2 min 3 sec / session
at 40.7 mW/cm²
PlatinumLED BIOMAX 300
480 · 630 · 660 · 810 · 830 · 850 · 1060 nm
Measured
$659
≈ 71 sec / session
at 70 mW/cm²

Matching a wavelength is not the same as reproducing a trial. Session times assume the device's published irradiance is accurate at the distance it was measured, which on brand-claim figures is often optimistic. Where a device publishes both a peak and an average we use the average, and where it publishes a falloff curve we use the lowest figure, so these times run long rather than short. Clinical protocols also control for spot size, contact and skin type in ways a home device cannot.

Source

Dosimetry extracted by Vladimir Heiskanen in Photobiomodulation (PBM) research - a comprehensive database. Citation resolved against PubMed.