redlight.store

🧑 Human 📄 Non-controlled, single-blind, crossover 👥 10 participants ⌛ 5 weeks · 2021 · USA (Boston, MA)

Pilot Study on Dose-Dependent Effects of Transcranial Photobiomodulation on Brain Electrical Oscillations: A Potential Therapeutic Target in Alzheimer's Disease

Spera · J Alzheimers Dis · 2021

The protocol this study used

Wavelength
830 nm
Dose
65.8 J/cm²
Sessions
1
Per session
20 min

What the authors concluded

c-tPBM significantly boosted gamma (t = 3.02, df = 7, p < 0.02) and beta (t = 2.91, df = 7, p < 0.03) EEG spectral powers in eyes-open recordings and gamma power (t = 3.61, df = 6, p < 0.015) in eyes-closed recordings, with a widespread increase over frontal-central scalp regions. There was no significant effect of tPBM on CBF compared to sham." "Our data suggest a dose-dependent effect of tPBM

Devices that emit this wavelength

Matched on wavelength within 15nm, since LED bins vary by roughly that much and a tighter match would be false precision. Where we have an irradiance figure, the session length is the time needed to reach this study's dose of 65.8 J/cm² at that intensity.

DISCLOSURE — we earn commission on purchases made through our links, at no extra cost to you. Rankings come from specifications and measurements, never from commission rates.

MitoPRO 1500+
630 · 660 · 830 · 850 nm
Measured
$1,169
≈ 14 min 20 sec / session
at 76.5 mW/cm²
MitoPRO 1500X
590 · 630 · 660 · 810 · 830 · 850 nm
Measured
$1,299
≈ 20 min 30 sec / session
at 53.5 mW/cm²
PlatinumLED BIOMAX 900
480 · 630 · 660 · 810 · 830 · 850 · 1060 nm
Measured
$1,299
≈ 12 min 9 sec / session
at 90.3 mW/cm²
MitoADAPT MAX 4.0
590 · 630 · 660 · 670 · 810 · 830 · 850 · 940 nm
Measured
$1,499
≈ 22 min 12 sec / session
at 49.4 mW/cm²
MitoADAPT MIN 4.0
590 · 630 · 660 · 670 · 810 · 830 · 850 · 940 nm
Measured
$549
≈ 26 min 57 sec / session
at 40.7 mW/cm²
PlatinumLED BIOMAX 300
480 · 630 · 660 · 810 · 830 · 850 · 1060 nm
Measured
$659
≈ 15 min 40 sec / session
at 70 mW/cm²

Matching a wavelength is not the same as reproducing a trial. Session times assume the device's published irradiance is accurate at the distance it was measured, which on brand-claim figures is often optimistic. Where a device publishes both a peak and an average we use the average, and where it publishes a falloff curve we use the lowest figure, so these times run long rather than short. Clinical protocols also control for spot size, contact and skin type in ways a home device cannot.

Source

PubMed 34092636 →

Dosimetry extracted by Vladimir Heiskanen in Photobiomodulation (PBM) research - a comprehensive database. Citation resolved against PubMed.