🐁 Mouse + 🧪 In vitro · 2021 · China (Guangzhou)
Photobiomodulation therapy for hair regeneration: A synergetic activation of β-CATENIN in hair follicle stem cells by ROS and paracrine WNTs
Jin · Stem Cell J · 2021
The protocol this study used
What the authors concluded
In mouse, the second telogen in back skin lasts about 6 weeks starting from the seventh week of life (Müller-Röver et al., 2001). To test whether PBMT affected HF regeneration, daily PBMT (635 nm, 6.67 mW/cm2 for 20 min, the dose reaching the epidermis was 8 J/cm2) stimulation to the back skin was initiated on postnatal day 50 for 14 consecutive days (Figure 1A). New anagen phase activation, char
Devices that emit this wavelength
Matched on wavelength within 15nm, since LED bins vary by roughly that much and a tighter match would be false precision. Where we have an irradiance figure, the session length is the time needed to reach this study's dose of 8 J/cm² at that intensity.
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Matching a wavelength is not the same as reproducing a trial. Session times assume the device's published irradiance is accurate at the distance it was measured, which on brand-claim figures is often optimistic. Where a device publishes both a peak and an average we use the average, and where it publishes a falloff curve we use the lowest figure, so these times run long rather than short. Clinical protocols also control for spot size, contact and skin type in ways a home device cannot.
Source
Dosimetry extracted by Vladimir Heiskanen in Photobiomodulation (PBM) research - a comprehensive database. Citation resolved against PubMed.