🐀 Rat · 2025 · Brazil (São Paulo)
Photobiomodulation presents an anti-inflammatory effect, reflecting on the expression of receptors related to the pain process in a collagenase-induced tendinitis experimental model
Silva · J Photochem Photobiol B · 2025
The protocol this study used
What the authors concluded
Our results showed that treatment with PBM reduced MPO activity and gene expression of B1, NK-1, GABAα2 receptors, as well as increased mechanical allodynia and GABAα1 expression. PBM + DZP also reduced MPO activity, as well as the expression of B1, GABAα₁ receptors and improved mechanical allodynia. The FLU+PBM group altered the results presented by the single treatment with PBM.
Devices that emit this wavelength
Matched on wavelength within 15nm, since LED bins vary by roughly that much and a tighter match would be false precision. Where we have an irradiance figure, the session length is the time needed to reach this study's dose of 107 J/cm² at that intensity.
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Matching a wavelength is not the same as reproducing a trial. Session times assume the device's published irradiance is accurate at the distance it was measured, which on brand-claim figures is often optimistic. Where a device publishes both a peak and an average we use the average, and where it publishes a falloff curve we use the lowest figure, so these times run long rather than short. Clinical protocols also control for spot size, contact and skin type in ways a home device cannot.
Source
Dosimetry extracted by Vladimir Heiskanen in Photobiomodulation (PBM) research - a comprehensive database. Citation resolved against PubMed.