🧪 In vitro · 2018 · Austria (Graz)
Photobiomodulation (PBM) promotes angiogenesis in-vitro and in chick embryo chorioallantoic membrane model.
Winter · Sci Rep · 2018
The protocol this study used
What the authors concluded
In conclusion we demonstrated the stimulating effect of intensive LED light of 635 nm at a pulse frequency of 2.5 Hz and a duty cycle of 50% on the angiogenesis in-vitro as well as in-vivo by means of cell culture and CAM assay. Further research is needed to characterize the mechanistic basis of this observation.
Devices that emit this wavelength
Matched on wavelength within 15nm, since LED bins vary by roughly that much and a tighter match would be false precision. Where we have an irradiance figure, the session length is the time needed to reach this study's dose of 24 J/cm² at that intensity.
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Matching a wavelength is not the same as reproducing a trial. Session times assume the device's published irradiance is accurate at the distance it was measured, which on brand-claim figures is often optimistic. Where a device publishes both a peak and an average we use the average, and where it publishes a falloff curve we use the lowest figure, so these times run long rather than short. Clinical protocols also control for spot size, contact and skin type in ways a home device cannot.
Source
Dosimetry extracted by Vladimir Heiskanen in Photobiomodulation (PBM) research - a comprehensive database. Citation resolved against PubMed.