🧪 In vitro · 2026 · Brazil (Natal)
Photobiomodulation at 660 nm enhances proliferative activity while preserving viability in human endothelial cells in vitro
Albuquerque · Cell Tissue Bank · 2026
The protocol this study used
What the authors concluded
At 72 h, all irradiated groups showed significantly greater metabolic activity than the control group (1.0 J/cm2, p < 0.01; 4.0 and 7.5 J/cm2, p < 0.001), whereas viability remained high across all groups (> 95%), with no evidence of cytotoxicity. PBM redistributed cells toward proliferative phases, with a higher proportion of S-phase cells at 1.0 J/cm2 and greater accumulation in G2/M at 4.0 a
Devices that emit this wavelength
Matched on wavelength within 15nm, since LED bins vary by roughly that much and a tighter match would be false precision. Where we have an irradiance figure, the session length is the time needed to reach this study's dose of 1 J/cm² at that intensity.
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Matching a wavelength is not the same as reproducing a trial. Session times assume the device's published irradiance is accurate at the distance it was measured, which on brand-claim figures is often optimistic. Where a device publishes both a peak and an average we use the average, and where it publishes a falloff curve we use the lowest figure, so these times run long rather than short. Clinical protocols also control for spot size, contact and skin type in ways a home device cannot.
Source
Dosimetry extracted by Vladimir Heiskanen in Photobiomodulation (PBM) research - a comprehensive database. Citation resolved against PubMed.