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🧪 In vitro · 2026 · Brazil (Natal)

Photobiomodulation at 660 nm enhances proliferative activity while preserving viability in human endothelial cells in vitro

Albuquerque · Cell Tissue Bank · 2026

The protocol this study used

Wavelength
660 nm
Dose
1 J/cm²
Sessions
—
Per session
—

What the authors concluded

At 72 h, all irradiated groups showed significantly greater metabolic activity than the control group (1.0 J/cm2, p < 0.01; 4.0 and 7.5 J/cm2, p < 0.001), whereas viability remained high across all groups (> 95%), with no evidence of cytotoxicity. PBM redistributed cells toward proliferative phases, with a higher proportion of S-phase cells at 1.0 J/cm2 and greater accumulation in G2/M at 4.0 a

Devices that emit this wavelength

Matched on wavelength within 15nm, since LED bins vary by roughly that much and a tighter match would be false precision. Where we have an irradiance figure, the session length is the time needed to reach this study's dose of 1 J/cm² at that intensity.

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MitoPRO 1500+
630 · 660 · 830 · 850 nm
Measured
$1,169
≈ 13 sec / session
at 76.5 mW/cm²
MitoPRO 1500X
590 · 630 · 660 · 810 · 830 · 850 nm
Measured
$1,299
≈ 19 sec / session
at 53.5 mW/cm²
PlatinumLED BIOMAX 900
480 · 630 · 660 · 810 · 830 · 850 · 1060 nm
Measured
$1,299
≈ 11 sec / session
at 90.3 mW/cm²
HoogaHealth PRO1500
660 · 850 nm
Measured
$1,199
≈ 12 sec / session
at 86 mW/cm²
Joovv Solo 3.0
660 · 850 nm
Measured
$1,499
≈ 17 sec / session
at 59.2 mW/cm²
LUMEBOX 2.0
660 · 850 nm
Measured
$629
≈ 8 sec / session
at 125 mW/cm²

Matching a wavelength is not the same as reproducing a trial. Session times assume the device's published irradiance is accurate at the distance it was measured, which on brand-claim figures is often optimistic. Where a device publishes both a peak and an average we use the average, and where it publishes a falloff curve we use the lowest figure, so these times run long rather than short. Clinical protocols also control for spot size, contact and skin type in ways a home device cannot.

Source

PubMed 42484713 →

Dosimetry extracted by Vladimir Heiskanen in Photobiomodulation (PBM) research - a comprehensive database. Citation resolved against PubMed.