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🧪 In vitro · 2017 · Brazil (Bauru)

Low level laser therapy modulates viability, alkaline phosphatase and matrix metalloproteinase-2 activities of osteoblasts.

Oliveira · J Photochem Photobiol B · 2017

The protocol this study used

Wavelength
660, 780 nm
Dose
1.9 J/cm²
Sessions
—
Per session
—

What the authors concluded

In conclusion, when used at these specific parameters, LLL modulates both preosteoblast viability and differentiation highlighted by the increased ALP and MMP-2 activities induced by irradiation.

Devices that emit this wavelength

Matched on wavelength within 15nm, since LED bins vary by roughly that much and a tighter match would be false precision. Where we have an irradiance figure, the session length is the time needed to reach this study's dose of 1.9 J/cm² at that intensity.

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MitoPRO 1500+
630 · 660 · 830 · 850 nm
Measured
$1,169
≈ 25 sec / session
at 76.5 mW/cm²
MitoPRO 1500X
590 · 630 · 660 · 810 · 830 · 850 nm
Measured
$1,299
≈ 36 sec / session
at 53.5 mW/cm²
PlatinumLED BIOMAX 900
480 · 630 · 660 · 810 · 830 · 850 · 1060 nm
Measured
$1,299
≈ 21 sec / session
at 90.3 mW/cm²
HoogaHealth PRO1500
660 · 850 nm
Measured
$1,199
≈ 22 sec / session
at 86 mW/cm²
Joovv Solo 3.0
660 · 850 nm
Measured
$1,499
≈ 32 sec / session
at 59.2 mW/cm²
LUMEBOX 2.0
660 · 850 nm
Measured
$629
≈ 15 sec / session
at 125 mW/cm²

Matching a wavelength is not the same as reproducing a trial. Session times assume the device's published irradiance is accurate at the distance it was measured, which on brand-claim figures is often optimistic. Where a device publishes both a peak and an average we use the average, and where it publishes a falloff curve we use the lowest figure, so these times run long rather than short. Clinical protocols also control for spot size, contact and skin type in ways a home device cannot.

Source

PubMed 28264787 →

Dosimetry extracted by Vladimir Heiskanen in Photobiomodulation (PBM) research - a comprehensive database. Citation resolved against PubMed.