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🧑 Human ⚔ Comparison study, randomized, crossover, double-blind 👥 48 participants ⌛ 6 weeks (2 x 3 weeks, no washout) · 2004 · Austria (Vienna)

Low level laser therapy in primary Raynaud's phenomenon--results of a placebo controlled, double blind intervention study.

Hirschl · J Rheumatol · 2004

The protocol this study used

Wavelength
640, 685 nm
Dose
2 J/cm²
Sessions
15
Per session
—

What the authors concluded

Intensity of attacks was only slightly reduced during placebo phase (about 96% of pretreatment intensity), while laser therapy resulted in a highly significant reduction to about 82%, with a decreasing trend during the 3-week therapy period. Although all thermographic measures compared favorably for laser therapy, none of them reached statistical significance (Table 2)." Comment: Parameters were

Devices that emit this wavelength

Matched on wavelength within 15nm, since LED bins vary by roughly that much and a tighter match would be false precision. Where we have an irradiance figure, the session length is the time needed to reach this study's dose of 2 J/cm² at that intensity.

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MitoPRO 1500+
630 · 660 · 830 · 850 nm
Measured
$1,169
≈ 26 sec / session
at 76.5 mW/cm²
MitoPRO 1500X
590 · 630 · 660 · 810 · 830 · 850 nm
Measured
$1,299
≈ 37 sec / session
at 53.5 mW/cm²
PlatinumLED BIOMAX 900
480 · 630 · 660 · 810 · 830 · 850 · 1060 nm
Measured
$1,299
≈ 22 sec / session
at 90.3 mW/cm²
MitoADAPT MAX 4.0
590 · 630 · 660 · 670 · 810 · 830 · 850 · 940 nm
Measured
$1,499
≈ 40 sec / session
at 49.4 mW/cm²
MitoADAPT MIN 4.0
590 · 630 · 660 · 670 · 810 · 830 · 850 · 940 nm
Measured
$549
≈ 49 sec / session
at 40.7 mW/cm²
PlatinumLED BIOMAX 300
480 · 630 · 660 · 810 · 830 · 850 · 1060 nm
Measured
$659
≈ 29 sec / session
at 70 mW/cm²

Matching a wavelength is not the same as reproducing a trial. Session times assume the device's published irradiance is accurate at the distance it was measured, which on brand-claim figures is often optimistic. Where a device publishes both a peak and an average we use the average, and where it publishes a falloff curve we use the lowest figure, so these times run long rather than short. Clinical protocols also control for spot size, contact and skin type in ways a home device cannot.

Source

PubMed 15570642 →

Dosimetry extracted by Vladimir Heiskanen in Photobiomodulation (PBM) research - a comprehensive database. Citation resolved against PubMed.