🧑 Human ⚔ Comparison study, randomized, crossover, double-blind 👥 48 participants ⌛ 6 weeks (2 x 3 weeks, no washout) · 2004 · Austria (Vienna)
Low level laser therapy in primary Raynaud's phenomenon--results of a placebo controlled, double blind intervention study.
Hirschl · J Rheumatol · 2004
The protocol this study used
What the authors concluded
Intensity of attacks was only slightly reduced during placebo phase (about 96% of pretreatment intensity), while laser therapy resulted in a highly significant reduction to about 82%, with a decreasing trend during the 3-week therapy period. Although all thermographic measures compared favorably for laser therapy, none of them reached statistical significance (Table 2)." Comment: Parameters were
Devices that emit this wavelength
Matched on wavelength within 15nm, since LED bins vary by roughly that much and a tighter match would be false precision. Where we have an irradiance figure, the session length is the time needed to reach this study's dose of 2 J/cm² at that intensity.
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Matching a wavelength is not the same as reproducing a trial. Session times assume the device's published irradiance is accurate at the distance it was measured, which on brand-claim figures is often optimistic. Where a device publishes both a peak and an average we use the average, and where it publishes a falloff curve we use the lowest figure, so these times run long rather than short. Clinical protocols also control for spot size, contact and skin type in ways a home device cannot.
Source
Dosimetry extracted by Vladimir Heiskanen in Photobiomodulation (PBM) research - a comprehensive database. Citation resolved against PubMed.