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🧪 In vitro · 2012 · Turkey (Ankara)

Low-level laser irradiation affects the release of basic fibroblast growth factor (bFGF), insulin-like growth factor-I (IGF-I), and receptor of IGF-I (IGFBP3) from osteoblasts.

Saygun · Photomed Laser Surg · 2012

The protocol this study used

Wavelength
685 nm
Dose
2 J/cm²
Sessions
1
Per session
2 min 20 sec

What the authors concluded

The results of the present study indicate that LLLT increases the proliferation of osteoblast cells and stimulates the release of bFGF, IGF-I, and IGFBP3 from these cells. The biostimulatory effect of LLLT may be related to the enhanced production of the growth factors.

Devices that emit this wavelength

Matched on wavelength within 15nm, since LED bins vary by roughly that much and a tighter match would be false precision. Where we have an irradiance figure, the session length is the time needed to reach this study's dose of 2 J/cm² at that intensity.

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MitoADAPT MAX 4.0
590 · 630 · 660 · 670 · 810 · 830 · 850 · 940 nm
Measured
$1,499
≈ 40 sec / session
at 49.4 mW/cm²
MitoADAPT MIN 4.0
590 · 630 · 660 · 670 · 810 · 830 · 850 · 940 nm
Measured
$549
≈ 49 sec / session
at 40.7 mW/cm²
Rouge Pro G4
630 · 650 · 660 · 670 · 810 · 830 · 850 · 1060 nm
Measured
$1,121
≈ 34 sec / session
at 59.2 mW/cm²
Theradome PRO LH80
680 nm
Brand claim
$845.99
no irradiance published
EMR-TEK Firewave
630 · 670 · 830 nm
Brand claim
$312.49
≈ 14 sec / session
at 138.39 mW/cm²
MitoADAPT MID 4.0
590 · 630 · 660 · 670 · 810 · 830 · 850 · 940 nm
Brand claim
$999
≈ 34 sec / session
at 58 mW/cm²

Matching a wavelength is not the same as reproducing a trial. Session times assume the device's published irradiance is accurate at the distance it was measured, which on brand-claim figures is often optimistic. Where a device publishes both a peak and an average we use the average, and where it publishes a falloff curve we use the lowest figure, so these times run long rather than short. Clinical protocols also control for spot size, contact and skin type in ways a home device cannot.

Source

PubMed 22235971 →

Dosimetry extracted by Vladimir Heiskanen in Photobiomodulation (PBM) research - a comprehensive database. Citation resolved against PubMed.