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🧑 Human 🎲 Randomized trial, double-blind 👥 50 participants ⌛ 2-week treatment / 1-year follow-up · 1999 · Austria (Vienna)

Low-intensity laser therapy is an effective treatment for recurrent herpes simplex infection. Results from a randomized double-blind placebo-controlled study.

Schindl & Neumann · J Invest Dermatol · 1999

The protocol this study used

Wavelength
690 nm
Dose
48 J/cm²
Sessions
2
Per session
10 min

What the authors concluded

The median recurrence-free interval in the laser-treated group was 37.5 wk (range: 2-52 wk) and in the placebo group 3 wk (range: 1-20 wk). This difference was found to be statistically significant (p < 0.0001; Wilcoxon's Rank Sum Test). In conclusion, we demonstrated that a total of 10 irradiations with low-intensity laser therapy significantly lowers the incidence of local recurrence of herpes

Devices that emit this wavelength

Matched on wavelength within 15nm, since LED bins vary by roughly that much and a tighter match would be false precision. Where we have an irradiance figure, the session length is the time needed to reach this study's dose of 48 J/cm² at that intensity.

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Theradome PRO LH80
680 nm
Brand claim
$845.99
no irradiance published
Theradome EVO LH40
680 nm
Not published
$695
no irradiance published

Matching a wavelength is not the same as reproducing a trial. Session times assume the device's published irradiance is accurate at the distance it was measured, which on brand-claim figures is often optimistic. Where a device publishes both a peak and an average we use the average, and where it publishes a falloff curve we use the lowest figure, so these times run long rather than short. Clinical protocols also control for spot size, contact and skin type in ways a home device cannot.

Source

Dosimetry extracted by Vladimir Heiskanen in Photobiomodulation (PBM) research - a comprehensive database. Citation resolved against PubMed.