redlight.store

🐀 Rat · 2016 · Brazil (Londrina)

Effects of the led therapy on the global DNA methylation and the expression of Dnmt1 and Dnmt3a genes in a rat model of skin wound healing.

Gomes · Lasers Med Sci · 2016

The protocol this study used

Wavelength
604 nm
Dose
0.8 J/cm²
Sessions
—
Per session
—

What the authors concluded

Based on our findings, we propose that DNA methylation is an important molecular mechanism associated to wound healing and that irradiation with 1.6 J/cm(2) of LED evokes an increase in the expression of the Dnmt3a that might associates to the efficiency of the epithelial wound healing.

Devices that emit this wavelength

Matched on wavelength within 15nm, since LED bins vary by roughly that much and a tighter match would be false precision. Where we have an irradiance figure, the session length is the time needed to reach this study's dose of 0.8 J/cm² at that intensity.

DISCLOSURE — we earn commission on purchases made through our links, at no extra cost to you. Rankings come from specifications and measurements, never from commission rates.

MitoPRO 1500X
590 · 630 · 660 · 810 · 830 · 850 nm
Measured
$1,299
≈ 15 sec / session
at 53.5 mW/cm²
MitoADAPT MAX 4.0
590 · 630 · 660 · 670 · 810 · 830 · 850 · 940 nm
Measured
$1,499
≈ 16 sec / session
at 49.4 mW/cm²
MitoADAPT MIN 4.0
590 · 630 · 660 · 670 · 810 · 830 · 850 · 940 nm
Measured
$549
≈ 20 sec / session
at 40.7 mW/cm²
MitoPRO 300X
590 · 630 · 660 · 810 · 830 · 850 nm
Measured
$449
≈ 15 sec / session
at 51.8 mW/cm²
Block Blue Light ULTIMATE XXL
590 · 630 · 650 · 810 · 830 · 850 · 1060 nm
Measured
$4499.95
≈ 11 sec / session
at 75 mW/cm²
Block Blue Light PowerPanel MAX
590 · 630 · 650 · 810 · 830 · 850 · 1060 nm
Brand claim
$1099.95
≈ 10 sec / session
at 82 mW/cm²

Matching a wavelength is not the same as reproducing a trial. Session times assume the device's published irradiance is accurate at the distance it was measured, which on brand-claim figures is often optimistic. Where a device publishes both a peak and an average we use the average, and where it publishes a falloff curve we use the lowest figure, so these times run long rather than short. Clinical protocols also control for spot size, contact and skin type in ways a home device cannot.

Source

Dosimetry extracted by Vladimir Heiskanen in Photobiomodulation (PBM) research - a comprehensive database. Citation resolved against PubMed.