🧑 Human 🎲 Randomized trial, crossover 👥 22 participants ⌛ 2 sessions with 1-week interval (active or control) · 2018 · Netherlands (Nijmegen)
Effects of red light on inflammation and skin barrier recovery following acute perturbation. Pilot study results in healthy human subjects.
Falcone · Photodermatol Photoimmunol Photomed · 2018
The protocol this study used
What the authors concluded
Firstly, red light at low fluence (3.6 J/cm 2 ) decreased the redness induced by histamine iontophoresis at 30 minutes after stimulus, in line with the use of red light in accelerating the resolution of erythema following skin rejuventation treatments ( 5). This effect was not observed with red light at higher fluence (30 J/cm 2 ) , possibly because of the greater increase in skin temperature lea
Devices that emit this wavelength
Matched on wavelength within 15nm, since LED bins vary by roughly that much and a tighter match would be false precision. Where we have an irradiance figure, the session length is the time needed to reach this study's dose of 3.6 J/cm² at that intensity.
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Matching a wavelength is not the same as reproducing a trial. Session times assume the device's published irradiance is accurate at the distance it was measured, which on brand-claim figures is often optimistic. Where a device publishes both a peak and an average we use the average, and where it publishes a falloff curve we use the lowest figure, so these times run long rather than short. Clinical protocols also control for spot size, contact and skin type in ways a home device cannot.
Source
Dosimetry extracted by Vladimir Heiskanen in Photobiomodulation (PBM) research - a comprehensive database. Citation resolved against PubMed.