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🐁 Mouse · 2021 · Korea (Seoul)

Effect of low-level laser intervention on dermatitis symptoms and cytokine changes in DNCB-induced atopy mouse model: A randomized controlled trial

Kim · Exp Ther Med · 2021

The protocol this study used

Wavelength
650 nm
Dose
2 J/cm²
Sessions
14
Per session
—

What the authors concluded

The results demonstrated that serum IgE level in all irradiated groups was significantly decreased compared with that of the AD control group, and IL-4 level was significantly decreased in all irradiated groups apart from the 8 J/cm2 LLL irradiated group. IL-6 and TNF-α levels were also significantly decreased in all irradiated groups. The results from histological analysis revealed diminished ep

Devices that emit this wavelength

Matched on wavelength within 15nm, since LED bins vary by roughly that much and a tighter match would be false precision. Where we have an irradiance figure, the session length is the time needed to reach this study's dose of 2 J/cm² at that intensity.

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MitoPRO 1500+
630 · 660 · 830 · 850 nm
Measured
$1,169
≈ 26 sec / session
at 76.5 mW/cm²
MitoPRO 1500X
590 · 630 · 660 · 810 · 830 · 850 nm
Measured
$1,299
≈ 37 sec / session
at 53.5 mW/cm²
PlatinumLED BIOMAX 900
480 · 630 · 660 · 810 · 830 · 850 · 1060 nm
Measured
$1,299
≈ 22 sec / session
at 90.3 mW/cm²
HoogaHealth PRO1500
660 · 850 nm
Measured
$1,199
≈ 23 sec / session
at 86 mW/cm²
Joovv Solo 3.0
660 · 850 nm
Measured
$1,499
≈ 34 sec / session
at 59.2 mW/cm²
LUMEBOX 2.0
660 · 850 nm
Measured
$629
≈ 16 sec / session
at 125 mW/cm²

Matching a wavelength is not the same as reproducing a trial. Session times assume the device's published irradiance is accurate at the distance it was measured, which on brand-claim figures is often optimistic. Where a device publishes both a peak and an average we use the average, and where it publishes a falloff curve we use the lowest figure, so these times run long rather than short. Clinical protocols also control for spot size, contact and skin type in ways a home device cannot.

Source

PubMed 34584541 →

Dosimetry extracted by Vladimir Heiskanen in Photobiomodulation (PBM) research - a comprehensive database. Citation resolved against PubMed.