🧑 Human 📄 Single-arm trial 👥 42 participants ⌛ single session · 2021 · Brazil (Rio de Janeiro)
Effect of 660/850 nm LED on the microcirculation of the foot: neurovascular biphasic reflex
de Sá CMD · Lasers Med Sci · 2021
The protocol this study used
What the authors concluded
The LED was applied on the right foot of forty-two normal volunteers followed by serial infrared images." "After the stimulus, a biphasic hyperthermia curve was observed synchronously in both feet, in the right and left halluxes, while hyperthermia was attributed to the redistribution of postural blood flow in the plantar region, which may indicate independent neurovascular mechanisms. Thus, per
Devices that emit this wavelength
Matched on wavelength within 15nm, since LED bins vary by roughly that much and a tighter match would be false precision. Where we have an irradiance figure, the session length is the time needed to reach this study's dose of 3.8 J/cm² at that intensity.
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Matching a wavelength is not the same as reproducing a trial. Session times assume the device's published irradiance is accurate at the distance it was measured, which on brand-claim figures is often optimistic. Where a device publishes both a peak and an average we use the average, and where it publishes a falloff curve we use the lowest figure, so these times run long rather than short. Clinical protocols also control for spot size, contact and skin type in ways a home device cannot.
Source
Dosimetry extracted by Vladimir Heiskanen in Photobiomodulation (PBM) research - a comprehensive database. Citation resolved against PubMed.