Augmenting Internet-Based Cognitive Behavioral Therapy for Major Depressive Disorder With Transcranial Infrared Laser Stimulation

What the authors concluded

There was a 43% reduction in Quick Inventory of Depressive Symptomatology-Self-Report scores in the sham group from the initial score to the week 12 score, while adding TILS as an adjunct therapy resulted in a reduction of 56%. Therefore, TILS resulted in an additional 30% reduction in Quick Inventory of Depressive Symptomatology-Self-Report scores ([56-43]/43 = 30%). Participants who received

Devices that emit this wavelength

Matched on wavelength within 15nm, since LED bins vary by roughly that much and a tighter match would be false precision. Where we have an irradiance figure, the session length is the time needed to reach this study's dose of 60 J/cm² at that intensity.

Matching a wavelength is not the same as reproducing a trial. Session times assume the device's published irradiance is accurate at the distance it was measured, which on brand-claim figures is often optimistic. Where a device publishes both a peak and an average we use the average, and where it publishes a falloff curve we use the lowest figure, so these times run long rather than short. Clinical protocols also control for spot size, contact and skin type in ways a home device cannot.