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🧑 Human 🎲 Randomized trial, double-blind, self-controlled 👥 76 participants ⌛ 4-week treatment / 4-month study · 2007 · Korea (Seoul)

A prospective, randomized, placebo-controlled, double-blinded, and split-face clinical study on LED phototherapy for skin rejuvenation: clinical, profilometric, histologic, ultrastructural, and biochemical evaluations and comparison of three different treatment settings.

Lee · J Photochem Photobiol B · 2007

The protocol this study used

Wavelength
633, 830 nm
Dose
66 J/cm²
Sessions
8
Per session
20 min

What the authors concluded

Our study results showed that LED phototherapy is an effective treatment for skin rejuvenation through objectively measured data and histological and ultrastructural bodies of evidence of increased collagen and elastic fibers as well as clinical photographs and double-blinded assessment of the investigators and the subjects.

Devices that emit this wavelength

Matched on wavelength within 15nm, since LED bins vary by roughly that much and a tighter match would be false precision. Where we have an irradiance figure, the session length is the time needed to reach this study's dose of 66 J/cm² at that intensity.

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MitoPRO 1500+
630 · 660 · 830 · 850 nm
Measured
$1,169
≈ 14 min 23 sec / session
at 76.5 mW/cm²
MitoPRO 1500X
590 · 630 · 660 · 810 · 830 · 850 nm
Measured
$1,299
≈ 20 min 34 sec / session
at 53.5 mW/cm²
PlatinumLED BIOMAX 900
480 · 630 · 660 · 810 · 830 · 850 · 1060 nm
Measured
$1,299
≈ 12 min 11 sec / session
at 90.3 mW/cm²
MitoADAPT MAX 4.0
590 · 630 · 660 · 670 · 810 · 830 · 850 · 940 nm
Measured
$1,499
≈ 22 min 16 sec / session
at 49.4 mW/cm²
MitoADAPT MIN 4.0
590 · 630 · 660 · 670 · 810 · 830 · 850 · 940 nm
Measured
$549
≈ 27 min 2 sec / session
at 40.7 mW/cm²
PlatinumLED BIOMAX 300
480 · 630 · 660 · 810 · 830 · 850 · 1060 nm
Measured
$659
≈ 15 min 43 sec / session
at 70 mW/cm²

Matching a wavelength is not the same as reproducing a trial. Session times assume the device's published irradiance is accurate at the distance it was measured, which on brand-claim figures is often optimistic. Where a device publishes both a peak and an average we use the average, and where it publishes a falloff curve we use the lowest figure, so these times run long rather than short. Clinical protocols also control for spot size, contact and skin type in ways a home device cannot.

Source

PubMed 17566756 →

Dosimetry extracted by Vladimir Heiskanen in Photobiomodulation (PBM) research - a comprehensive database. Citation resolved against PubMed.