🧑 Human 🎲 Randomized trial, double-blind, self-controlled 👥 76 participants ⌛ 4-week treatment / 4-month study · 2007 · Korea (Seoul)
A prospective, randomized, placebo-controlled, double-blinded, and split-face clinical study on LED phototherapy for skin rejuvenation: clinical, profilometric, histologic, ultrastructural, and biochemical evaluations and comparison of three different treatment settings.
Lee · J Photochem Photobiol B · 2007
The protocol this study used
What the authors concluded
Our study results showed that LED phototherapy is an effective treatment for skin rejuvenation through objectively measured data and histological and ultrastructural bodies of evidence of increased collagen and elastic fibers as well as clinical photographs and double-blinded assessment of the investigators and the subjects.
Devices that emit this wavelength
Matched on wavelength within 15nm, since LED bins vary by roughly that much and a tighter match would be false precision. Where we have an irradiance figure, the session length is the time needed to reach this study's dose of 66 J/cm² at that intensity.
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Matching a wavelength is not the same as reproducing a trial. Session times assume the device's published irradiance is accurate at the distance it was measured, which on brand-claim figures is often optimistic. Where a device publishes both a peak and an average we use the average, and where it publishes a falloff curve we use the lowest figure, so these times run long rather than short. Clinical protocols also control for spot size, contact and skin type in ways a home device cannot.
Source
Dosimetry extracted by Vladimir Heiskanen in Photobiomodulation (PBM) research - a comprehensive database. Citation resolved against PubMed.